Correlação entre parâmetros bioquímicos séricos e composição do colostro e do leite de suínas lactantes

José de Arimatéia de Freitas Pinto; Pedro Henrique da Silva Fidelis; João Paulo Bezerra Saraiva; Radan Elvis Matias Oliveira; Amanda Medeiros Araújo de Oliveira; Adriano  Henrique do Nascimento Rangel; Michelly Fernandes de Macedo; Rennan Herculano Rufino Moreira

doi:10.1590/1983-21252025v3812911rc

Authors

José de Arimatéia de Freitas Pinto Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0002-3425-9972
Pedro Henrique da Silva Fidelis Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0002-1760-6311
João Paulo Bezerra Saraiva Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0001-5947-6810
Radan Elvis Matias Oliveira Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0002-0370-4447
Amanda Medeiros Araújo de Oliveira Department of Animal Science, Universidade Federal do Ceará, Fortaleza, CE, Brazil https://orcid.org/0000-0001-7349-5559
Adriano Henrique do Nascimento Rangel Academic Unit Specialized in Agricultural Sciences, Universidade Federal do Rio Grande do Norte, Macaíba, RN, Brazil https://orcid.org/0000-0002-2835-4156
Michelly Fernandes de Macedo Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0001-9571-9816
Rennan Herculano Rufino Moreira Postgraduate Program in Animal Production, Department of Animal Science, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil https://orcid.org/0000-0001-7144-5750

DOI:

https://doi.org/10.1590/1983-21252025v3812911rc

Keywords:

Monitoring. Sows. Animal production. Animal health.

Abstract

Monitoring the serum biochemical parameters of sows' blood, colostrum, and milk during and after calving aims to guide and understand the physiological, nutritional, and health status of peri-calving sows. Thus, this study aimed to analyze and correlate serum biochemical parameters and the composition of colostrum and milk of lactating sows. Colostrum, milk, and blood from 13 sows were collected after the birth of the first calf before suckling (M1) and 72 hours after M1 (M2). Crude protein (CP), fat content (FAT), lactose (LAC), nonfat solids (NFS), total solids (TS), and gamma-glutamyltransferase (GGT) activity concentrations were determined in colostrum and milk samples. The blood biochemical profiles analyzed were GGT, glucose (GLU), total cholesterol (COL), triglycerides (TRI), creatine kinase (CK), total protein (TP), albumin (ALB), globulins (GLO), and the albumin/globulin ratio (A/G). Descriptive and correlation analyses were performed using the SAS statistical program (9.3). Significant differences were observed in the composition of colostrum and milk. COL and CK in the blood showed significant differences between M1 and M2. There was no correlation (P>0.05) between serum biochemical and colostrum bromatological parameters. ALB correlated positively with LAC and NFS. GLO correlated negatively with LAC and NFS. The A/G ratio showed a positive correlation with LAC. These correlations suggest that monitoring serum biochemical parameters may be helpful for the health surveillance of lactating sows and assessing the quality of colostrum and milk.

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References

BAROZA, P. F. J. et al. Perfil bioquímico e proteinograma do soro lácteo de cabras e vacas nos primeiros 30 dias após o parto. Medicina Veterinária, 13: 498-505, 2019.

BELINSKAIA, D. A.; VORONINA, P. A.; GONCHAROV, N. V. Integrative Role of Albumin: Evolutionary, Biochemical and Pathophysiological Aspects. Journal of Evolutionary Biochemistry and Physiology, 57: 1419-1448, 2021.

CHEN, J. et al. The Effects of Dietary Supplementation of Saccharomyces cerevisiae Fermentation Product During Late Pregnancy and Lactation on Sow Productivity, Colostrum and Milk Composition, and Antioxidant Status of Sows in a Subtropical Climate. Frontiers in Veterinary Science, 7: 1-9, 2020.

DJOKOVIC, R. et al. Relationship among Blood Indicators of Hepatic Function and Lipid Content in the Liver during Transitional Period in High-Yielding Dairy Cows. Acta Scientiae Veterinariae, 41: 1-6, 2013.

GOECKE, N. B. et al. Objective pathogen monitoring in nursery and finisher pigs by monthly laboratory diagnostic testing. Porcine Health Management, 6: 1-14, 2020.

GONZÁLEZ, D. F. H.; SILVA, S. C. Introdução à bioquímica clínica veterinária. 3. ed. Porto Alegre, RS: Editora da UFRGS, 2017. 538 p.

HURLEY, W. L. Composition of sow colostrum and milk. In: FARMER, C. (Ed.). The Gestating and Lactating Sow. Wageningen, GE: Wageningen Academic Publishers, 2015. v. 1 , cap. 9, p. 193-229.

HURLEY, W. L.; THEIL, P. K. Perspectives on immunoglobulins in colostrum and milk. Nutrients, 3: 442-474, 2011.

INDRIO, F. et al. Development of the Gastrointestinal Tract in Newborns as a Challenge for an Appropriate Nutrition: A Narrative Review. Nutrients, 14: 1-14, 2022.

KANEKO, J. J.; HARVEY, J. W.; BRUSS, M. L. Clinical Biochemistry of Domestic Animals, 6. ed. San Diego, California: Academic Press, 2008. 916 p.

KOSTER, J. et al. Prediction of metabolic clusters in early-lactation dairy cows using models based on milk biomarkers. Journal of Dairy Science, 102: 2631-2644, 2019.

MACIAG, S. S. et al. On the influence of the source of porcine colostrum in the development of early immune ontogeny in piglets. Scientific Reports, 12: 1-16, 2022.

MARTIN, C. R.; LING, P. R.; BLACKBURN, G. L. Review of infant feeding: key features of breast milk and infant formula. Nutrients, 8: 1-11, 2016.

MOHAMED, G. A. E. Investigation of some enzymes level in blood and milk serum in two stages of milk yield dairy cows at assiut city. Assiut Veterinary Medical Journal, 60: 110-120, 2014.

MOREIRA, R. H. R. et al. Variability of piglet birth weights: A systematic review and meta‐analysis. Journal of Animal Physiology and Animal Nutrition, 104: 657-666, 2019.

MUKAKA, M. M. Statistics corner: A guide to appropriate use of correlation coefficient in medical research. Malawi Medical Journal, 24: 69-71, 2012.

MUNS, R.; NUNTAPAITOON, M.; TUMMARUK, P. Non-infectious causes of pre-weaning mortality in piglets. Livestock Science, 184: 46-57, 2016.

NOZAD, S. et al. Relationship between blood urea, protein, creatinine, triglycerides and macro-mineral concentrations with the quality and quantity of milk in dairy Holstein cows. Veterinary Research Forum, 3: 55-59, 2007.

PEDERSEN, L. J. Overview of commercial pig production systems and their main welfare challenges. In: CAMERLINK, I.; BAXTER, E. M. (Eds.). Advances in Pig Welfare. Cambridge, United Kingdom: Woodhead Publishing, 2018. cap. 1, p. 3-25.

PELTONIEMI, O. et al. Coping with large litters: the management of neonatal piglets and sow reproduction. Journal of Animal Science and Technology, 63: 1–15, 2021.

QUESNEL, H.; FARMER, C.; DEVILLERS, N. Colostrum intake: Influence on piglet performance and factors of variation. Livestock Science, 146: 105-114, 2012.

ROTHKÖTTER, H. J.; SOWA, E.; PABST, R. The pig as a model of developmental immunology. Human & Experimental Toxicology, 21: 533-536, 2002.

THEIL, P. K.; LAURIDSEN, C.; QUESNEL, H. Neonatal piglet survival: impact of sow nutrition around parturition on fetal glycogen deposition and production and composition of colostrum and transient milk. Animal, 8:1021-1030, 2014.

THEIL, P. K. et al. Mechanistic model to predict colostrum intake based on deuterium oxide dilution technique data and impact of gestation and prefarrowing diets on piglet intake and sow yield of colostrum. Journal of Animal Science, 92: 5507-5519, 2014.

THEIL, P. K.; HURLEY, W. L. The protein component of sow colostrum and milk. In: GIGLI, I. (Ed.). Milk proteins: from structure to biological properties and health aspects. Rijeka, HRV: IntechOpen, 2016, v. 1, cap. 9, p. 183-198.

TIAN, Z. et al. Transcriptional regulation of milk fat synthesis in dairy cattle. Journal of Functional Foods, 96: 1-8, 2022.

TOPIGS NORSVIN. TN70 FEED MANUAL: Tips and advice for TN70, 2023. Available at: . Access on: May. 30, 2024

TSAI, Y. J. et al. Monitoring the lactation-related behaviors of sows and their piglets in farrowing crates using deep learning. Frontiers in Animal Science, 5: 1-16, 2024.

YAN, L.; MENG, Q. W.; KIM, I. H. Effect of an herb extract mixture on growth performance, nutrient digestibility, blood characteristics, and fecal microbial shedding in weanling pigs. Livestock Science, 145: 189-195, 2012.

ZANELLO. G. et al. Effects of dietary yeast strains on immunoglobulin in colostrum and milk of sows. Veterinary Immunology and Immunopathology, 152: 20-27, 2013.