Comparison among effects of different treatments for second intention skin healing in sheep

Authors

  • José Eduardo Barroso Machado
  • Fábio Henrique Bezerra Ximenes
  • Ceci Ribeiro Leite
  • Vanessa da Silva Mustafa
  • José Renato Junqueira Borges
  • Márcio Botelho Castro
  • Roberta Ferro de Godoy

DOI:

https://doi.org/10.21708/avb.2010.4.4.1675

Abstract

Wound treatment in sheep is an issue that brings many doubts for practitioners due to the great number of products available in the market with different chemical compositions and concentrations. Among the main products used in clinical and surgical routine, iodine povidone solutions, chlorate compounds (Dakin solution) and phytotherapic products such as those produced from Stryphnodendron adstringens peel are the most common. Aiming to prove the macroscopic and microscopic effects of these treatments, an experimental assay was performed using six rams of Santa Inês breed aging approximately one year old. Wounds were produced surgically with a circular punch in the thoracic region and the cicatricial evolution by second intention was observed. Macroscopic parameters evaluated were local hemorrhage, clots, scabs, granulation tissue, epitelization and exsudate. In the microscopic analysis of the biopsies, fibrosis, reepitelization, vascularization, mononuclear infiltrates, polimorphonuclear exsudates, edema and ulceration were evaluated. The data was statistically analyzed. Macroscopically the best treatment was pure water which was used as a control treatment. Microscopically, the best results were achieved in the wounds treated with Dakin solution. Keywords: Antiseptic, tissue repair, Stryphnodendron adstringens.

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Published

2010-12-20

Issue

Section

Original Articles / Artigos de Pesquisa

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